You can configure proxies between various Trend Micro components. For details, see
Configure proxies.
Use proxy server
To view and edit the list of available proxies, go to Administration > System Settings > Proxies. The following options are available:
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Primary Security Update Proxy used by Agents, Appliances, and Relays (see Connect to the Primary Security Update Source via proxy)
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Deep Security Manager (Connection to Trend Micro services) (see Connect to Deep Security Software Updates, CSSS, and more via proxy)
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Deep Security Manager (Cloud Accounts - HTTP Protocol Only) (see Connect to cloud accounts via proxy)
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Trend Vision One Endpoint Security Link (HTTP Protocol Only) (see Connect to Workload Security via proxy)