For on-premises Trend Micro products to make Smart Protection queries against the Smart Protection Server in the Service Gateway, configure the Smart Protection Server in your product's console using the Service Gateway's setting. For detailed instructions, look for topics related to configuring Smart Protection in your product's documentation.
Examples:
Apex One: Use the Service Gateway's endpoint name or IPv4/IPv6 address in the standard list of Smart Protection sources.
Deep Discovery Inspector: Use the Service Gateway's IPv4 address in the Smart Protection Server List.
https://docs.trendmicro.com/en-us/enterprise/deep-discovery-inspector.aspx
Deep Discovery Analyzer: Use the Service Gateway's IPv4 address in the Smart Protection Server List.
https://docs.trendmicro.com/en-us/enterprise/deep-discovery-analyzer.aspx