The OfficeScan server is the standard update source for agents.
If the OfficeScan server is unreachable, agents will not have a backup source and will therefore remain outdated. To update agents that cannot reach the OfficeScan server, Trend Micro recommends using Agent Packager. Use this tool to create a package with the latest components available on the server and then run the package on agents.
The agent’s IP address (IPv4 or IPv6) determines if connection to the OfficeScan server can be established. For details about IPv6 support for agent updates, see IPv6 Support for OfficeScan Agent Updates.