A pure IPv6 agent cannot update directly from pure IPv4 update sources, such as:
A pure IPv4 OfficeScan server
A pure IPv4 Update Agent
Any pure IPv4 custom update source
Trend Micro ActiveUpdate Server
Similarly, a pure IPv4 agent cannot update directly from pure IPv6 update sources, such as a pure IPv6 OfficeScan server or Update Agent.
A dual-stack proxy server that can convert IP addresses, such as DeleGate, is required to allow the agents to connect to the update sources.