Most OfficeScan agent features available on Windows Server 2008/2012/2016 work on Server Core. The only feature that is not supported is Independent mode.
For a list of features available on Windows Server 2008/2012/2016, see OfficeScan Agent Features.
The OfficeScan agent console is only accessible from the command line interface.
Some OfficeScan agent console screens include a Help button, which, when clicked, opens context-sensitive, HTML-based Help. Because Windows Server Core 2008/2012/2016 lack a browser, the Help will not be available to the user. To view the Help, the user must install a browser.