You
               can install the integrated or standalone Smart Protection Server
               if the number of 
clients is
               1,000 or less. Install a standalone Smart Protection Server if there
               are more than 1,000 
clients.
            
 
            Trend Micro recommends
               installing several Smart Protection Servers for failover purposes. Clients that are
               unable to connect to a particular server will try to connect to
               the other servers you have set up.
            
            Because the integrated server and the OfficeScan server
               run on the same computer, the computer’s performance may reduce
               significantly during peak traffic for the two servers. Consider
               using a standalone Smart Protection Server as the primary smart
               protection source for clients and
               the integrated server as a backup.